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Our health may not only be affected by chemical contaminants present in our food- or environment, but also by compounds that contaminate consumer products and/or food packaging materials, and may migrate under specific conditions. Examples of consumer product-related chemicals that are under suspicion for their potential health effects are certain plasticizers, PFASs, brominated dioxins and fire-retardants. CALUX® assays can be used to control and monitor consumer safety e.g. in combination with migration studies for monitoring release of bioactive compounds from a packaging material, or for consumer product safety testing, with a focus on endocrine activity, geno- and cytotoxicity related effects.