Good predictivity of in vivo effects is essential for successful application of an alternative testing battery. BDS spends a considerable amount of effort in quality control of its assays, validation and incorporation in international guidelines. As such, OECD and ISO guidelines are available that include validated CALUX® assay protocols, and BDS is actively engaged in promoting further regulatory acceptance of these novel approaches, which are generally considered as the way forward in safety evaluation. A wide range of references is available to support the excellent performance of our assays (please see News and Downloads section).